Impact of Positive Family History and Genetic Risk Variants on the Incidence of Diabetes The Finnish Diabetes Prevention Study
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چکیده
RESEARCH DESIGN AND METHODS—A total of 522 subjects with impaired glucose tolerance (IGT) were randomized into the control (n = 257) and intervention (n = 265) groups. The mean follow-up was 6.2 years (median 7 years), and the lifestyle intervention, aimed at weight reduction, healthy diet, and increased physical activity, lasted for 4 years (range 1–6 years). An oral glucose tolerance test (OGTT) and assessment of basic clinical variables were performed annually.
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پیشگیری اولیه از دیابت نوع 2
The incidence and prevalence of type2 diabetes mellitus is increasing worldwide. Many believe that type 2 diabetes mellitus is a disease that can be prevented by appropriate interventions in individuals at high risk for the disease. A number of studies have therefore looked at primary prevention during the past decade. Iran’s diabetic population of approximately 2 million people and the warn...
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Background: Pre-diabetes is a high risk condition for developing type 2 diabetes mellitus and cardiovascular disease. The target of this study is evaluation of incidence rate of pre-diabetes and its risk factors in a long- term follow up in the Tehran Lipid and Glucose Study. Methods: The Tehran Lipid and Glucose Study is a prospective study being accomplished on a characteristic sample of t...
متن کاملImpact of Positive Family History and Genetic Risk Variants on the Incidence of Diabetes
OBJECTIVE We aimed to investigate the influence of positive family history (FH+) of diabetes and 19 known genetic risk loci on the effectiveness of lifestyle changes and their predictive value on the incidence of type 2 diabetes in the Finnish Diabetes Prevention Study (DPS). RESEARCH DESIGN AND METHODS A total of 522 subjects with impaired glucose tolerance (IGT) were randomized into the con...
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متن کاملA Survey on Prevalence of Ocular Complications and It’s Risk Factors in Diabetic Patients of Diabetic Center of Nader Kazemi Clinic Shiraz- Iran 1998-2010
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تاریخ انتشار 2011